Early Infant Feeding Practices May Influence the Onset of Symptomatic Celiac Disease / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition
;
: 229-235, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-190328
ABSTRACT
PURPOSE:
To study whether breastfeeding and breastfeeding status during gluten introduction influences the age at diagnosis of celiac disease (CD). In addition to study, whether the timing of gluten introduction influences the age at diagnosis of CD.METHODS:
It was a hospital based observational study. Total 198 patients diagnosed with CD as per modified European Society of Pediatric Gastroenterology, Hepatology and Nutrition (2012) criteria, aged between 6 months to 6 years were included. Detail history taken with special emphasis on breastfeeding and age of gluten introduction. Standard statistical methods used to analyze the data.RESULTS:
Mean±standard deviation age of onset and diagnosis of CD in breastfed cases was 2.81±1.42 years and 3.68 ±1.55 years respectively as compared to 1.84±1.36 years and 2.70±1.65 years respectively in not breastfed cases (p<0.05). Those who had continued breastfeeding during gluten introduction and of longer duration had significantly delayed onset of disease. The age at onset of CD was under one year in 40.42% of the cases, who had started gluten before 6 months of age compared to only 12.58% of those who had started gluten later (p<0.001). The proposed statistical model showed that two variables, i.e., breast feeding status during gluten introduction and age at gluten introduction positively influencing the age at diagnosis of CD.CONCLUSION:
Delayed gluten introduction to infant's diet along with continuing breastfeeding, delays symptomatic CD. However, it is not clear from our study that these infant feeding practices provide permanent protection against the disease or merely delays the symptoms.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Allaitement naturel
/
Maladie coeliaque
/
Modèles statistiques
/
Âge de début
/
Diagnostic
/
Régime alimentaire
/
Étude d'observation
/
Gastroentérologie
/
Glutens
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
/
Bébé
langue:
Anglais
Texte intégral:
Pediatric Gastroenterology, Hepatology & Nutrition
Année:
2016
Type:
Article
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