A Case of Familial Clustering of Hepatitis C Virus / 대한소아소화기영양학회지
Korean Journal of Pediatric Gastroenterology and Nutrition
;
: 91-95, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-192637
ABSTRACT
The familial environment may also play an important role in the epidemiology of HCV infection through vertical and horizontal transmission by infected household members. However, it is still controversial whether familial clustering of HCV occurs. We experienced a case of familial clustering of hepatitis C virus. A 10-year old girl presented with nausea, vomiting and anorexia for a month was diagnosed as hepatitis C. Her mother, grandmother, a maternal aunt and her daughter had contracted with HCV. Her laboratory findings showed AST/ALT 63/122 IU/L, positive anti-HCV Ab and HCV RNA (3.54 x 10(5) copies/mL). Pathologic findings of the liver biopsy revealed chronic hepatitis with minimal lobular activity, mild porto-periportal activity and mild portal fibrosis. After treatment with interferon-alpha 2b for 6 months, the clinical symptoms and laboratory findings were normalized.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Vomissement
/
Biopsie
/
Fibrose
/
ARN
/
Famille nucléaire
/
Anorexie
/
Analyse de regroupements
/
Caractéristiques familiales
/
Épidémiologie
/
Interféron alpha
Limites du sujet:
Enfant
/
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Pediatric Gastroenterology and Nutrition
Année:
2005
Type:
Article
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