Visualization of endolymphatic hydrops using Magnetic Resonance Imaging after intratympanic Gd-DTPA administration in patients with Meniere's disease
Journal of the Korean Balance Society
;
: 167-173, 2008.
Article
Dans Coréen
| WPRIM
| ID: wpr-193990
ABSTRACT
BACKGROUND AND OBJECTIVES:
Endolymphatic hydrops are known as major causes of Meniere's disease. MRI (Magnetic resonance imaging) with contrast tried recently makes it possible to visualize perilymphatic and endolymphatic space without invasive procedures. There are no tryouts in the interior of our country. We attempted MRI after injection of gadolinium-diethylen-triamine pentaacetic acid (Gd-DTPA) in normal adults and patients with Meniere's disease to make sure 3D-FLAIR (fluid-attenuated inversion recovery) MRI parameters and to visualize endolymphatic spaces. MATERIALS ANDMETHODS:
Five normal adults and Five patients with Meniere's disease were included in this study. Twenty-four hours after Gd-DTPA intratympanic injection, we performed 3D-FLAIR and 3D-IR imaging at 3T. MRI region of interest signal intensity was used to determine the diffusion of Gd-DTPA into the perilymphatic fluid spaces over time.RESULTS:
Five of five in normal group, using 3D-IR MRI after Gd injection, had enhanced imagings (perilymphatic spaces) of inner ears. Five of five in patients group, using 3D-IR after Gd injection, had enhanced perilymphatic spaces and non-enhanced endolymphatic hydrops.CONCLUSIONS:
Delayed contrast imaging of the inner ear with 3D-IR MRI after Gd-DTPA intratympanic injection revealed in vivo visualization of endolymphatic hydrops.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Imagerie par résonance magnétique
/
Spectroscopie par résonance magnétique
/
Hydrops endolymphatique
/
Acide gadopentétique
/
Diffusion
/
Aimants
/
Oreille interne
/
Magnétisme
/
Maladie de Ménière
Limites du sujet:
Adulte
/
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Balance Society
Année:
2008
Type:
Article
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