Use of Splenectomy to Treat Evans Syndrome Following an ABO-Matched Liver Transplant / 대한내과학회지
Korean Journal of Medicine
;
: 464-468, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-194216
ABSTRACT
Evans syndrome is a rare complication that develops in adults after liver transplantation. The possible etiologies include ABO mismatch, viral infection, post-transplantation lymphoproliferative disease, graft-versus-host disease, and the use of certain immunosuppressive drugs (e.g., calcineurin inhibitors). Here, we present a case of Evans syndrome that developed after an ABO-matched liver transplant. Glucocorticosteroid, intravenous immunoglobulin, and alternative immunosuppressant therapies all failed. Weekly rituximab (375 mg/m2) was then administered for 4 weeks. The cytopenia improved transiently after the second dose of rituximab, but soon worsened again. However, the cytopenia normalized after a splenectomy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Splénectomie
/
Immunoglobulines
/
Transplantation hépatique
/
Purpura thrombopénique idiopathique
/
Calcineurine
/
Rituximab
/
Maladie du greffon contre l'hôte
/
Anémie hémolytique auto-immune
/
Foie
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
Korean Journal of Medicine
Année:
2015
Type:
Article
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