Small Increases in Plasma Sodium Are Associated with Higher Risk of Mortality in a Healthy Population
Journal of Korean Medical Science
;
: 1034-1040, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-196069
ABSTRACT
Elevated blood pressure (BP) is the most common cause of cardiovascular disease. Salt intake has a strong influence on BP, and plasma sodium (pNa) is increased with progressive increases in salt intake. However, the associations with pNa and BP had been reported inconsistently. We evaluated the association between pNa and BP, and estimated the risks of all-cause-mortality according to pNa levels. On the basis of data collected from health checkups during 1995-2009, 97,009 adult subjects were included. Positive correlations between pNa and systolic BP, diastolic BP, and pulse pressure (PP) were noted in participants with pNa > or =138 mM/L (P or =50 yr, SBP, DBP, and PP were positively associated with pNa. In participants with metabolic syndrome components, the differences in SBP and DBP according to pNa were greater (P or =50 yr during the median 4.2-yr-follow-up (P or =145 mM/L was related to mortality. The positive correlation between pNa and BP is stronger in older subjects, women, and subjects with metabolic syndrome components. The incidence and adjusted risks of mortality increase with increasing pNa in women aged > or =50 yr.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Sodium
/
Pression sanguine
/
Maladies cardiovasculaires
/
Facteurs sexuels
/
Risque
/
Incidence
/
Facteurs de risque
/
Syndrome métabolique X
/
Hypertension artérielle
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Journal of Korean Medical Science
Année:
2013
Type:
Article
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