Successful desensitization for cytarabine induced anaphylaxis
Allergy, Asthma & Respiratory Disease
;
: 394-397, 2014.
Article
Dans Coréen
| WPRIM
| ID: wpr-197342
ABSTRACT
Cytarabine is a very important chemotherapeutic agent for leukemia and lymphoma patients and is prescribed more frequently than before. Cytarabine-induced delayed-onset hypersensitivity may rarely present as non-IgE mediated anaphylaxis. However, we do not know yet whether desensitization therapy in adults may be effective in cytarabine-induced delayed-onset anaphylaxis. A 78-year-old woman who was diagnosed with acute myeloblastic leukemia had chemotherapy including cytarabine. In spite of premedication with hydrocortisone and chlorpheniramine, the patient had anaphylaxis a few hours after cytarabine infusion. We decided to perform desensitization therapy. After desensitization therapy using a newly designed protocol, the patient was tolerable to cytarabine infusion without hypotension or high fever. Desensitization therapy was successfully performed on an adult patient with delayed-onset anaphylaxis caused by cytarabine.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prémédication
/
Hydrocortisone
/
Leucémie aigüe myéloïde
/
Leucémies
/
Chlorphénamine
/
Désensibilisation immunologique
/
Cytarabine
/
Traitement médicamenteux
/
Fièvre
/
Hypersensibilité
Type d'étude:
Guide de pratique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Allergy, Asthma & Respiratory Disease
Année:
2014
Type:
Article
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