Chemical Constituents of Fermented Noni (Morinda citrifolia) Juice Exudates and Their Biological Activity
Natural Product Sciences
;
: 16-20, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-198627
ABSTRACT
In a continuing study of the fermented noni (Morinda citrifolia) juice exudates, five compounds, heptanyl 2-O-β-D-xylofuranosyl-(1 → 6)-β-D-glucopyranoside (1), n-butyl β-D-glucopyranoside (2), (1S)-(3-ethenyl-phenyl)-1,2-ethanediol (3), (2S)-2-hydroxybutanedioic acid (4), and daucosterol (5) were isolated from the buthanol partition of the extract. The structures of the isolates were identified by 1D and 2D NMR, and MS experiments, as well as by comparison of their data with the published values. Among the isolates, compounds 1 – 3 were isolated for the first time from the plant species. The isolated compounds were evaluated for their cancer chemopreventive potential based on their ability to inhibit nitric oxide (NO) production and tumor necrosis factor alpha (TNF-α)-induced NF-κB activity, and quinonone reductase-1 (QR1)-inducing effect.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plantes
/
Facteur de nécrose tumorale alpha
/
Rubiaceae
/
Morinda
/
Exsudats et transsudats
/
Monoxyde d'azote
Type d'étude:
Étude pronostique
langue:
Anglais
Texte intégral:
Natural Product Sciences
Année:
2017
Type:
Article
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