Meconium Peritonitis: 15 Cases Studies

ABSTRACT

PURPOSE: Meconium peritonitis is a form of aseptic, chemical peritonitis that results from a perforation of the gut during the intrauterine or perinatal period. The rarity of the disease resulted in few survivors up to the 1950's. However, the constantly increasing survival rate has followed an aggressive surgical management, along with a more thorough understanding of the etiological and pathological variations likely to be encountered. This study was performed to analyze our past 10 years' experience with meconium peritonitis. METHODS: The hospital records of 15 patients treated between January 1991 to December 2000 were retrospectively reviewed. RESULTS: The male to female sex ratio was 21, and the age at surgery varied from at the time of birth to 48 days. The clinical manifestations included marked abdominal distension (13 cases), respiratory distress (8 cases), billous vomiting (5 cases) and scrotal swelling (1 case). Radiological findings included air-fluid level (7 cases), calcification (4 cases) and pneumoperitoneum (3 cases). The prenatal ultrasonography demonstrated dilated loops of bowel, septated fetal ascites and calcification. The leading cause of perforation was small bowel atresia (8 cases). A primary end-to-end anastomosis was performed in 10 cases. Generalized type (8 cases) was the most common finding of meconium peritonitis. 86% of patients survived without long-term complications. CONCLUSION: Early recognition and proper management offer the greatest opportunity for survival in cases of meconium peritonitis.