An Adolescent Ischemic Stroke Patient with Hyperhomocysteinemia, MTHFR 677TT and CBS 1080TT genotypes
Journal of the Korean Neurological Association
;
: 382-385, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-201279
ABSTRACT
Hyperhomocysteinemia is an independent risk factor for cerebrovascular disease. Hyperhomocysteinemia can be caused by the defect of the remethylation pathway including the 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene or the transsulfuration pathway including the cystathionine beta-synthase (CBS) gene of homocysteine metabolism. The major cause of severe hyperhomocysteinemia is CBS gene mutation. A 16-year-old male was admitted with vertigo. Brain MRI showed right cerebellar infarction. The plasma homocysteine level was 175 mocro mol/L. According to a genetic evaluation, the patient had the MTHFR 677TT and CBS 1080TT genotypes.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Oxidoreductases
/
Plasma sanguin
/
Encéphale
/
Imagerie par résonance magnétique
/
Vertige
/
Facteurs de risque
/
Hyperhomocystéinémie
/
Accident vasculaire cérébral
/
Cystathionine beta-synthase
/
Génotype
Type d'étude:
Etude d'étiologie
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Journal of the Korean Neurological Association
Année:
2005
Type:
Article
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