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Intravitreal Bevacizumab Injection in Adult Coats' Disease
Journal of the Korean Ophthalmological Society ; : 630-634, 2009.
Article Dans Coréen | WPRIM | ID: wpr-201701
ABSTRACT

PURPOSE:

To report the efficacy of intravitreal bevacizumab injection in adult patients with Coats' disease. CASE

SUMMARY:

Vascular telangiectasia, microaneurysms, circinate hard exudates, and macular edema were shown in the macula of two patients. Vascular abnormality was limited to < or =6 clock hours in both cases. In case 1, the temporal retina demonstrates filigree-like vessels and capillary nonperfusion. In case 2, the nasal retina demonstrates aneurysmal dilatation and multiple microaneurysms. Intravitreal bevacizumab injection was administered in both cases. After 1 month, macular edema decreased. Laser photocoagulation was performed for vascular telangiectasia, microaneurysms, and capillary nonperfusion area. Then an additional decrease of macular edema was observed. Fluorescein leakage decreased, as well. After 1 month (case 1) and 2 months (case 2), macular edema increased. The second and third intravitreal reinjections were administered to each patient. Macular edema decreased.

CONCLUSIONS:

We report two rare cases of Coats' disease in adult patients. Intravitreal bevacizumab injection in patients with Coats' disease can result in a rapid decrease of macular edema, which will then lead to rapid visual recovery and an opportunity for effective laser photocoagulation. We recommend that intraviteal bevacizumab injection be used in combination with laser photocoagulation for the treatment of Coats' disease.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Rétine / Télangiectasie / Vaisseaux capillaires / Oedème maculaire / Fluorescéine / Dilatation / Exsudats et transsudats / Anticorps monoclonaux humanisés / Bévacizumab / Anévrysme Limites du sujet: Adulte / Humains langue: Coréen Texte intégral: Journal of the Korean Ophthalmological Society Année: 2009 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Rétine / Télangiectasie / Vaisseaux capillaires / Oedème maculaire / Fluorescéine / Dilatation / Exsudats et transsudats / Anticorps monoclonaux humanisés / Bévacizumab / Anévrysme Limites du sujet: Adulte / Humains langue: Coréen Texte intégral: Journal of the Korean Ophthalmological Society Année: 2009 Type: Article