The Relationship between Serum Adiponectin, Essential Hypertension, LV Mass Index, and LV Diastolic Function
Korean Circulation Journal
;
: 1126-1133, 2003.
Article
Dans Coréen
| WPRIM
| ID: wpr-202132
ABSTRACT
BACKGROUND AND OBJECTIVES:
Adiponectin is known for its anti-inflammatory and anti-atherogenic effects. The purpose of this study is to characterize the relationships among serum adiponectin, essential hypertension (EH), left ventricular mass index (LVMI), and LV diastolic function. SUBJECTS ANDMETHODS:
Serum adiponectin by RIA and body mass index were measured in 275 patients (M F=137 138). We calculated LVMI, E/A ratio, deceleration time (DT), and isovolumetric relaxation time (IVRT) by using echocardiograms.RESULTS:
The serum adiponectin level of the hypertensive group was significantly lower than that of the non-hypertensive group (9.9+/-9.8 ug/mL vs. 12.9+/-9.5 ug/mL, p<0.05). Plasma adiponectin was negatively correlated with LVMI (r=-0.329, p<0.001), BMI (r=-0.290, p<0.001), and IVRT (r=-0.485, p<0.05), but was positively correlated with E/A (r=+0.359, p<0.001).CONCLUSION:
These results suggest that a decrease in serum adiponectin is associated with an increase in blood pressure and BMI, progress of LVH, and decrease in LV diastolic function.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plasma sanguin
/
Relaxation
/
Pression sanguine
/
Indice de masse corporelle
/
Hypertrophie ventriculaire gauche
/
Décélération
/
Adiponectine
/
Hypertension artérielle
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Circulation Journal
Année:
2003
Type:
Article
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