Shear Wave Elastography for Detection of Prostate Cancer: A Preliminary Study
Korean Journal of Radiology
;
: 346-355, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-203185
ABSTRACT
OBJECTIVE:
To assess the diagnostic value of shear wave elastography (SWE) for prostate cancer detection. MATERIALS ANDMETHODS:
In this retrospective study, 87 patients with the suspicion of prostate cancer (prostate-specific antigen > 4 ng/mL and abnormal digital rectal examination) underwent a protocol-based systematic 12-core biopsy followed by targeted biopsy at hypoechoic areas on grey-scale ultrasound. Prior to biopsy, SWE was performed by placing two circular 5 mm-sized regions of interest (ROIs) along the estimated biopsy tract in each sector and one ROI for hypoechoic lesions. SWE parameters, S (mean stiffness) and R (mean stiffness ratio), were calculated and compared regarding different histopathologic tissues and their accuracy for diagnosing prostate cancer was analyzed. SWE parameters were correlated with Gleason score and were compared between indolent ( or = 8) tissues in prostate cancer patients.RESULTS:
Prostate cancer was detected in 7.5% of 1058 cores in 29.9% of 87 patients. Seven (43.8%) of 16 hypoechoic lesions were confirmed as prostate cancer. SWE parameters were significantly different among the histopathologic entities (p 43.9 kPa and 60.8%, 66.4%, and 0.653, respectively, for R > 3. Both, S and R showed a significant correlation with Gleason score (r > or = 0.296, p < or = 0.008) and were significantly different between indolent and aggressive prostate cancer (p < or = 0.006).CONCLUSION:
Shear wave elastographic parameters are significantly different between prostate cancer and benign prostate tissue and correlate with Gleason score.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prostate
/
Tumeurs de la prostate
/
Biopsie
/
Études rétrospectives
/
Courbe ROC
/
Sensibilité et spécificité
/
Antigène spécifique de la prostate
/
Échographie interventionnelle
/
Imagerie d'élasticité tissulaire
/
Grading des tumeurs
Type d'étude:
Etude diagnostique
/
Guide de pratique
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Aged80
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Korean Journal of Radiology
Année:
2014
Type:
Article
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