Mesalazine-induced Eosinophilic Pneumonia in a Patient with Crohn's Disease / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 116-120, 2009.
Article
Dans Coréen
| WPRIM
| ID: wpr-205448
ABSTRACT
Mesalazine (5-aminosalicylic acid) and sulfasalazine are widely used in the treatment of inflammatory bowel disease. The pulmonary toxicity related to sulfasalazine was well-recognized complication and it was caused by sulfapyridine moiety in sulfasalazine. However, the lung injury related to mesalazine has rarely been reported. A thirty five-year-old man with Crohn's disease who was treated with mesalazine complained fever and dry cough. The finding of bilateral wandering pulmonary infiltration, peripheral eosinophilia and increased eosinophils in bronchoalvolar lavage were consistent with eosinophilic pneumonia. His symptoms and laboratory findings were markedly improved after the discontinuation of mesalazine. The mesalazine-induced eosinophilic pneumonia was diagnosed according to his clinical course. This report shows that the eosinophilic pneumonia should be considered in patients who develope pulmonary involvement with inflammatory bowel disease receiving mesalazine therapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Poumon éosinophile
/
Activation des lymphocytes
/
Maladie de Crohn
/
Tomodensitométrie
/
Anti-inflammatoires non stéroïdiens
/
Mésalazine
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
The Korean Journal of Gastroenterology
Année:
2009
Type:
Article
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