A clinical study of testicular relapse in childhood acute lymphocytic leukemia
Journal of the Korean Pediatric Society
;
: 680-686, 1993.
Article
Dans Coréen
| WPRIM
| ID: wpr-206736
ABSTRACT
From January 1984 to June 1991, we studied testicular relapsed patients among 105 cases of acute lymphocytic leukemia in children who were admitted to the Department of Pediatrics and Yonsei Cancer Center, Yonsei University Severance Hospital. The results were as follows 1) 15 out of 105 (14.4%) cases of acute lymphocytic leukemia were diagnosed as testicular relapse. According to the prevalence by the age groups, there were no patient under 2 years old, 14 out of 73 (19.4%) in 2~9 years old and 1 out of 26 (3.8%) over 10 years old groups. 2) At initial diagnosis of acute lymphocytic leukemia there were significant correlation between testicular relapse and initial lymphadenopathy (p=0.09), but not with WBC count, hemoglobin level, platelet count, hepatomegaly and splenomegaly. 3) Mean duration to testicular relapse from initial diagnosis of acute lymphocytic leukemia was 3.1+/-1.7 years. 4) Among 15 patients, 7 cases combined with bone marrow or central nervous system relapse. Their survival rate was lower than isolated testicular relapse groups. 5) The 5 years survival rate of testicular relapsed patients was 67% after the combinations of chemotherapy, radiotherapy and orchiectomy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pédiatrie
/
Numération des plaquettes
/
Radiothérapie
/
Récidive
/
Splénomégalie
/
Moelle osseuse
/
Orchidectomie
/
Système nerveux central
/
Prévalence
/
Taux de survie
Type d'étude:
Etude diagnostique
/
Étude de prévalence
Limites du sujet:
Enfant
/
Enfant d'âge préscolaire
/
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Pediatric Society
Année:
1993
Type:
Article
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