Imatinib-induced Psoriasiform Drug Eruption in a Patient with a Gastrointestinal Stromal Tumor / 대한피부과학회지
Korean Journal of Dermatology
;
: 388-391, 2015.
Article
Dans Coréen
| WPRIM
| ID: wpr-206793
ABSTRACT
Imatinib mesylate (Gleevec(R)) is a small-molecule inhibitor that selectively inhibits the tyrosine kinase family, including mutated KIT oncoproteins in gastrointestinal stromal tumors (GIST). However, cutaneous reactions to imatinib are common and occur in 7.0% to 88.9% of patients. Nonspecific skin rashes, facial edema, and pruritus are the most common adverse reactions. However, development of psoriasiform drug eruption owing to the drug has rarely been reported. Herein we report on a 66-year-old male patient with GIST who had taken imatinib (400 mg/day) for 2 months. He developed erythematous scaly macules and papules on the trunk and extremities. Histopathological findings were compatible with a psoriasiform drug eruption.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Prurit
/
Psoriasis
/
Protein-tyrosine kinases
/
Protéines oncogènes
/
Toxidermies
/
Méthanesulfonates
/
Tumeurs stromales gastro-intestinales
/
Oedème
/
Exanthème
/
Membres
Limites du sujet:
Adulte très âgé
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Dermatology
Année:
2015
Type:
Article
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