A Case of von Hippel-Lindau Disease with Colorectal Adenocarcinoma, Renal Cell Carcinoma and Hemangioblastomas / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 409-414, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-20749
ABSTRACT
von Hippel-Lindau (VHL) disease is an autosomal dominant inherited tumor syndrome associated with mutations of the VHL tumor suppressor gene located on chromosome 3p25. The loss of functional VHL protein contributes to tumorigenesis. This condition is characterized by development of benign and malignant tumors in the central nervous system (CNS) and the internal organs, including kidney, adrenal gland, and pancreas. We herein describe the case of a 74-year-old man carrying the VHL gene mutation who was affected by simultaneous colorectal adenocarcinoma, renal clear cell carcinoma, and hemangioblastomas of CNS.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pancréas
/
Néphrocarcinome
/
Tumeurs colorectales
/
Adénocarcinome
/
Système nerveux central
/
Gènes suppresseurs de tumeur
/
Glandes surrénales
/
Hémangioblastome
/
Carcinogenèse
/
Maladie de von Hippel-Lindau
Limites du sujet:
Adulte très âgé
/
Humains
langue:
Anglais
Texte intégral:
Cancer Research and Treatment
Année:
2016
Type:
Article
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