Radiotherapy of Brain Metastases from Lung Cancer
Journal of Lung Cancer
;
: 34-37, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-207842
ABSTRACT
PURPOSE:
Brain metastasis is estimated to occur in 10~45% of solid cancer patients, and is the most common intracranial tumor in adults. Several neurologic symptom palliations are made with steroid therapy and whole brain irradiation. MATERIALS ANDMETHODS:
We evaluated respectively the clinical characteristics and treatment outcome for 44 patients with metastatic brain tumor from lung cancer during the period from April 2000 to December 2003.RESULTS:
Median age of the patients was 61 years. The male female ratio was 2.7 1. Synchronous and metachronous brain metastasis was seen in 18 (40.9%) and 26 patients (59.1%), respectively and median duration between the diagnosis of lung cancer and brain metastases was 6 months (range 1~18 months) in metachronous cases. Pathologic types of lung cancer were as follows small cell lung cancer in 11 patients and non-small cell lung cancer in 33 patients (squamous cell carcinoma-13, adenocarcinoma-11, large cell carcinoma- 3, others-6). The most common symptom of brain metastasis was headache, which was in 27 patients (61.4%). Seven patients (15.9%) had a single brain metastasis while 37 patients (84.1%) had multiple brain metastases. The total radiation dose to whole brain ranged from 30 to 40 Gy (median 30 Gy). In 29 patients (65.9%) neurological symptoms were resolved after whole brain irradiation. Median survival was 18 weeks for patients with steroid therapy and whole brain radiotherapy.CONCLUSION:
In present study, we confirmed that whole brain irradiation is an effective palliative treatment for patients with metastatic brain tumors from lung cancer
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Soins palliatifs
/
Radiothérapie
/
Encéphale
/
Tumeurs du cerveau
/
Résultat thérapeutique
/
Carcinome pulmonaire non à petites cellules
/
Diagnostic
/
Carcinome pulmonaire à petites cellules
/
Céphalée
/
Poumon
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Journal of Lung Cancer
Année:
2005
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS