A case of overlap syndrome of systemic sclerosis/ systemic lupus erythematosus/Sjogren's syndrome / 대한류마티스학회지

ABSTRACT

Overlap syndrome is a combination of major features of more than one rheumatic disease present in the same patient and often defined by a specific serologic test. Overlap syndrome consistent with systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) has been reported in a few cases. Overlap syndrome with SSc and SLE combined with Sjogren's syndrome (SS) is rarely reported worldwide. In Korea, this is the first case report. A 33 year-old female visited our rheumatology clinic complaining of Raynaud' s phenomenon. She was diagnosed as SSc 6 years ago. Clinical and laboratory finding revealed that she has affected by SLE. She also complained dry mouth and dry eye. Finally, she was diagnosed as overlap syndrome consistent with SSc and SLE combined with SS. The authors report a case of overlap syndrome consistent with SSc, SLE, and SS with relevant literatures.