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Refractory Duodenal Crohn's Disease Successfully Treated with Infliximab
Intestinal Research ; : 66-69, 2014.
Article Dans Anglais | WPRIM | ID: wpr-208946
ABSTRACT
Crohn's disease (CD) may involve any part of the gastrointestinal tract, from the mouth to the anus. Approximately >90% of cases occur in the small bowel and colon. Upper gastrointestinal involvement, especially duodenal manifestation, is relatively rare. Therefore, adequate medical treatment for duodenal CD has not yet been established. We report a case of CD with duodenal involvement. A 46-year-old man with Crohn's ileocolitis presented to our hospital with right upper quadrant pain. An endoscopy showed a deep excavated ulcer with deformity at the duodenal bulb, and he was initially treated with azathioprine (1 mg/kg), Pentasa (3.0 g/day), and a proton pump inhibitor for 1 year. However, the deep ulcer did not heal. Therefore, infliximab infusion therapy was initiated, and the duodenal lesion completely resolved on follow-up esophagogastroduodenoscopy. We report a case of duodenal CD that completely resolved following infliximab infusion, with a review of the literature.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Canal anal / Azathioprine / Malformations / Ulcère / Maladie de Crohn / Études de suivi / Endoscopie digestive / Pompes à protons / Côlon / Mésalazine Type d'étude: Étude observationnelle / Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Intestinal Research Année: 2014 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Canal anal / Azathioprine / Malformations / Ulcère / Maladie de Crohn / Études de suivi / Endoscopie digestive / Pompes à protons / Côlon / Mésalazine Type d'étude: Étude observationnelle / Étude pronostique Limites du sujet: Humains langue: Anglais Texte intégral: Intestinal Research Année: 2014 Type: Article