Relationship between the low-density lipoprotein cholesterol level and clinical outcome after percutaneous coronary intervention in patients with acute myocardial infarction / 대한내과학회지
Korean Journal of Medicine
; : 692-700, 2009.
Article
de Ko
| WPRIM
| ID: wpr-209001
Bibliothèque responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS: This study examined the relationship between the low-density lipoprotein cholesterol (LDL-C) level and clinical outcome after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). METHODS: Between January 2006 and December 2007, 867 patients (age, 62.6+/-12.5 years; males, 71%) undergoing a 1-year follow- up after PCI for AMI were divided into five groups according to the LDL-C level: or =160 mg/dL. RESULTS: Smoking (63%), hypertension (46%), and diabetes mellitus (28%) were common risk factors. The history of ischemic heart disease decreased as the LDL-C level increased (p=0.036). Patients with lower LDL-C levels had lower creatinine clearance and higher high-sensitivity C-reactive protein (hsCRP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels. The rate of in-hospital complications after PCI declined with increases in the LDL-C level, except in patients with LDL-C >160 mg/dL (linear p=0.010). There was no correlation between the LDL-C level and the 30-day or 1-year clinical outcome after PCI. After multivariate adjustment, independent predictors of the 1-year mortality after PCI were left ventricular ejection fraction, hsCRP, age, and creatinine clearance. CONCLUSIONS: Higher LDL-C levels were related to fewer in-hospital complications, but there was no correlation between the LDL-C level and long-term clinical outcome after PCI in Korean patients with AMI.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Fumée
/
Débit systolique
/
Protéine C-réactive
/
Fumer
/
Cholestérol
/
Facteurs de risque
/
Ischémie myocardique
/
Créatinine
/
Diabète
/
Intervention coronarienne percutanée
Type d'étude:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Humans
/
Male
langue:
Ko
Texte intégral:
Korean Journal of Medicine
Année:
2009
Type:
Article