Efficacy of 14 Day OBMT Therapy as a Second-line Treatment for Helicobacter pylori Infection / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 136-141, 2004.
Article
Dans Coréen
| WPRIM
| ID: wpr-213233
ABSTRACT
BACKGROUND/AIMS:
As a second-line treatment for H. pylori eradication in the case of first-line OAC (omeprazole, amoxicillin, clarithromycin) treatment failure, a minimum of one-week OBMT quadruple therapy composed of omeprazole, bismuth, metronidazole, tetracycline has been recommended in European countries and one or two weeks in USA. In Korea, one-week OBMT quadruple therapy is recommended for the case of first-line OAC treatment failure. Because H. pylori eradication rate of one-week OBMT therapy in Korea is about 80%, the eradication rate of one week therapy is not satisfactory. We analyzed the effect of two-week second-line OBMT therapy.METHODS:
Between June 2002 and June 2003, 107 patients who were H. pylori positive (44 males and 63 females mean age 51.8 years) after primary eradication therapy received two-week OBMT therapy. Four weeks after completion of therapy, 13C-urea breath test was performed to detect H. pylori.RESULTS:
After two weeks of OBMT therapy, eradication was achieved in 103 of 107 patients (96.3%) and in 68 of 71 peptic ulcer patients (95.8%).CONCLUSIONS:
Two-week OBMT therapy should be considered as a retreatment regimen with the eradication rate more than 90%.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tétracycline
/
Bismuth
/
Oméprazole
/
Résumé en anglais
/
Helicobacter pylori
/
Infections à Helicobacter
/
Reprise du traitement
/
Association de médicaments
/
Antiacides gastriques
/
Métronidazole
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
The Korean Journal of Gastroenterology
Année:
2004
Type:
Article
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