Two Cases of Allopurinol Hypersensitivity Syndrome in Patients Receiving Thiazide Therapy due to Hypertension / 대한피부과학회지
Korean Journal of Dermatology
; : 1426-1429, 2005.
Article
de Ko
| WPRIM
| ID: wpr-213602
Bibliothèque responsable:
WPRO
ABSTRACT
Allopurinol hypersensitiviy syndrome (AHS) is a rare immunologic response to allopurinol, characterized by multiple findings such as skin rash, fever, hepatic dysfunction, decreased renal function, leukocytosis and eosinophilia. The risk developing AHS tends to increase in patients receiving thiazide therapy or in those who have a pre-existing renal disease. We report two cases of AHS in patients who were taking thiazide medication due to hypertension and underlying renal disease. They developed an erythematous skin rash, fever, renal dysfunction, and eosinophilia after allopurionol therapy.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Allopurinol
/
Éosinophilie
/
Exanthème
/
Fièvre
/
Hypersensibilité
/
Hypertension artérielle
/
Hyperleucocytose
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Korean Journal of Dermatology
Année:
2005
Type:
Article