Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer
The World Journal of Men's Health
;
: 28-33, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-214132
ABSTRACT
PURPOSE:
The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival. MATERIALS ANDMETHODS:
Between January 2005 and July 2015, 71 patients at 6 institutions who had undergone penectomy or penile biopsy were enrolled. Their medical records were reviewed to identify the mode of therapy, pathology reports, and cancer-specific survival (CSS) rate.RESULTS:
Clinicopathologic and outcome information was available for 52 male patients (mean age, 64.3 years; mean follow-up, 61.4 months). At presentation, 17 patients were node-positive, and 4 had metastatic disease. Management was partial penectomy in 34 patients, total penectomy in 12 patients, and chemotherapy or radiotherapy in 6 patients. The pathology reports were squamous cell carcinoma in 50 patients and other types of carcinoma in the remaining 2 patients. Kaplan-Meier survival analysis showed a 5-year CSS rate of 84.0%. In univariate and multivariate analyses, the American Joint Committee on Cancer (AJCC) stage and pathologic grade were associated with survival.CONCLUSIONS:
Partial penectomy was the most common treatment of penile lesions. The oncologic outcomes were good, with a 5-year CSS of 84.0%. The AJCC stage and pathologic grade were independent prognostic factors for survival.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Tumeurs du pénis
/
Pronostic
/
Radiothérapie
/
Biopsie
/
Carcinome épidermoïde
/
Dossiers médicaux
/
Analyse multifactorielle
/
Études de suivi
/
Résultat thérapeutique
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
The World Journal of Men's Health
Année:
2017
Type:
Article
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