Peritoneal Dialysis-related Peritonitis in Children: A Single Center's Experience Over 12 Years
Journal of the Korean Society of Pediatric Nephrology
;
: 80-88, 2012.
Article
Dans Coréen
| WPRIM
| ID: wpr-215813
ABSTRACT
PURPOSE:
The aim of our study was to investigate the characteristics of the peritoneal dialysis (PD) - related peritonitis and to evaluate the effectiveness of the empirical antibiotics recommended by the International Society for Peritoneal Dialysis in Korean children.METHODS:
We retrospectively reviewed the medical records of 72 children on peritoneal dialysis at the Department of Pediatrics, Asan Medical Center over the period from March 2000 to February 2012.RESULTS:
Seventy-nine episodes of peritonitis occurred in 32 patients. The incidence of peritonitis was 0.43 episodes/patient.year. There were no significant differences in the incidence of peritonitis in terms of dialysis modality (P=0.459). Twenty-one patients experienced 51 catheter exit-site infections (0.28 episode/patient.year). There were no significant differences in the incidence of peritonitis between those with and without history of exit-site infections (P=0.721). Specific pathogens were isolated from 68.4% (54/79) of the patient with peritonitis episodes, including Gram-positive bacteria (n=34), Gram-negative bacteria (n=25) and fungus (n=1). Among Gram-positive bacteria, 85.3% of the isolates were susceptible to beta-lactam antibiotics, among Gram-negative rods, 94.7% of the isolates were susceptible to ceftazidime. Among 25 cases with unknown etiologies, 92.0% of cases demonstrated satisfactory responses to cefazolin and ceftazidime.CONCLUSIONS:
The incidence of peritonitis was 0.43 episodes/patient.year. Initial empirical therapy consisting of cefazolin and ceftazidime was appropriate for 91.1% of the PD-related peritonitis treatment. Continuous monitoring for the emergence of the resistant organisms is an important part of the appropriate managements of PD-related peritonitis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pédiatrie
/
Péritonite
/
Céfazoline
/
Ceftazidime
/
Dossiers médicaux
/
Incidence
/
Études rétrospectives
/
Dialyse péritonéale
/
Dialyse
/
Cathéters
Type d'étude:
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Enfant
/
Humains
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Journal of the Korean Society of Pediatric Nephrology
Année:
2012
Type:
Article
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