A Database of Gene Expression Profiles of Korean Cancer Genome
Genomics & Informatics
;
: 86-89, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-216093
ABSTRACT
Because there are clear molecular differences entailing different treatment effectiveness between Korean and non-Korean cancer patients, identifying distinct molecular characteristics of Korean cancers is profoundly important. Here, we report a web-based data repository, namely Korean Cancer Genome Database (KCGD), for searching gene signatures associated with Korean cancer patients. Currently, a total of 1,403 cancer genomics data were collected, processed and stored in our repository, an ever-growing database. We incorporated most widely used statistical survival analysis methods including the Cox proportional hazard model, log-rank test and Kaplan-Meier plot to provide instant significance estimation for searched molecules. As an initial repository with the aim of Korean-specific marker detection, KCGD would be a promising web application for users without bioinformatics expertise to identify significant factors associated with cancer in Korean.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Marqueurs biologiques
/
Expression des gènes
/
Modèles des risques proportionnels
/
Résultat thérapeutique
/
Génome
/
Biologie informatique
/
Génomique
/
Transcriptome
Type d'étude:
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Genomics & Informatics
Année:
2015
Type:
Article
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