Evaluation of Rapid Assay (Tox A/B Quik Chek) for the Detection of Clostridium difficile Toxins A and B / 대한임상미생물학회지
Korean Journal of Clinical Microbiology
;
: 112-116, 2008.
Article
Dans Coréen
| WPRIM
| ID: wpr-217983
ABSTRACT
BACKGROUND:
Toxin immunoassay is widely used for rapid diagnosis of Clostridium difficile-associated diarrhea. The aim of this study was to evaluate the performance of Tox A/B Quik Chek test (TECHLAB, Blacksburg, VA, USA) compared to toxigenic culture.METHODS:
From September 2006 to August 2007, 959 stools were examined by Tox A/B Quik Chek test and toxigenic culture (C. difficile culture plus tcdB PCR using colonies obtained from culture).RESULTS:
Compared to the results of toxigenic culture, the sensitivity and specificity of Tox A/B Quik Chek test were 47.5% and 97.5%, respectively.CONCLUSION:
The sensitivity of Tox A/B Quik Chek test was not high, but the specificity was high. Although Tox A/B Quik Chek test alone is not sufficient to diagnose Clostridium difficile-associated diarrhea, it may aid rapid diagnosis, early treatment and prevention of nosocomial spread of the infection, if supplemented by C. difficile culture or tissue culture cytotoxin assay.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Protéines bactériennes
/
Toxines bactériennes
/
Composés du bore
/
Dosage immunologique
/
Réaction de polymérisation en chaîne
/
Clostridioides difficile
/
Techniques immunoenzymatiques
/
Sensibilité et spécificité
/
Clostridium
/
Diagnostic précoce
Type d'étude:
Etude diagnostique
/
Étude de dépistage
langue:
Coréen
Texte intégral:
Korean Journal of Clinical Microbiology
Année:
2008
Type:
Article
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