Comparison of Three Assay Systems for Qualitative and Quantitative Results of Hepatitis B Surface Antibody / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 431-435, 2006.
Article
Dans Coréen
| WPRIM
| ID: wpr-223945
ABSTRACT
BACKGROUND:
With a technical improvement of the assay system, automated immunoassay analyzers for hepatitis B surface antibody (anti-HBs) are widely used. However, some discrepancies between assays are still being reported. We compared the qualitative and quantitative results of three kinds of anti-HBs assays.METHODS:
Serum samples were collected from 517 patients and anti-HBs were determined using AxSYM AUSAB, Bayer ADVIA Centaur, and Roche Elecsys assay systems.RESULTS:
The concordance rates between the three assays were 95.1% (543/571). The concordance rates were 97.7% between Centaur and Elecsys, 96.3% between AxSYM and Centaur, and 95.6% between AxSYM and Elecsys. Their correlation coefficients for quantitative results were 0.97, 0.94, and 0.93 in the same order. Twenty-eight specimens showed discrepant results, and all of them had antibody values below 31.5 mIU/mL.CONCLUSIONS:
Three immunoassays for anti-HBs presented a high concordance and correlation; however, the results should be interpreted with caution, because there were still significant differences between assay methods, especially for a low-level of anti-HBs.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Dosage immunologique
/
Virus de l'hépatite B
/
Hépatite
/
Hépatite B
Type d'étude:
Recherche qualitative
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
The Korean Journal of Laboratory Medicine
Année:
2006
Type:
Article
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