A case of anticonvulsant hypersensitivity syndrome with pseudolymphoma induced by carbamazepine / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 657-661, 2001.
Article
Dans Coréen
| WPRIM
| ID: wpr-223981
ABSTRACT
Anticonvulsant hypersensitivity syndrome(AHS) is an uncommon, but potentially fatal, multi-systemic disorder that occurs after exposure to phenytoin, carbamazepine, phenobarbital. Clinical features and laboratory data are diverse and variable. The multi-systemic reaction presents as fever, skin eruptions, lymphadenopathy, hematologic abnormality, and hepatitis. It is postulated that this mechanism can cause deficient enzymatic reduction by epoxide hydrolase. The diagnosis of AHS is made by reviewing the history of drug exposure and clinical course. It is important to discontinue use of the offending drug suspected for AHS and to closely observe patients with anticonvulsant therapy. We experienced a case of anticonvulsant hypersensitivity syndrome developed by carbama-zepine, presented with pseudolymphoma in lymph node biopsy and improved by discontinuing the drug and implementing steroid treatment. We report this case with pathologic findings and a brief review.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Phénobarbital
/
Phénytoïne
/
Peau
/
Biopsie
/
Carbamazépine
/
Pseudolymphome
/
Diagnostic
/
Fièvre
/
Hépatite
/
Hypersensibilité
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of Asthma, Allergy and Clinical Immunology
Année:
2001
Type:
Article
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