Discoid Lupus Erythematosus-like Eruption Induced by Tegafur - Uracil (UFT) / 대한피부과학회지
Korean Journal of Dermatology
;
: 1004-1007, 2010.
Article
Dans Coréen
| WPRIM
| ID: wpr-225088
ABSTRACT
The second-generation oral anticancer agent UFT is a combination of uracil, which has fluorouracil's (5-FU) degradation-inhibitory effect, and tegafur, which is slowly converted to 5-FU in vivo, and UFT shows a higher 5-FU concentration in the tumor tissues than is achieved by tegafur alone or with comparable doses of intravenous 5-FU. Mucocutaneous side reactions induced by UFT are rare and these include photosensitivity of the lichenoid and eczematous types, acral erythema, hyperpigmentation, palmoplantar keratoderma and scleroderma-like reactions, and discoid lupus erythematosus (DLE)-like eruption. However, there has been no report in the Korean medical literature on patients presenting with a DLE-like eruption associated with UFT. So, we report here a case of DLE-like eruption induced by oral UFT.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Uracile
/
Lupus érythémateux chronique
/
Tégafur
/
Hyperpigmentation
/
Kératose palmoplantaire
/
Érythème
/
Fluorouracil
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Dermatology
Année:
2010
Type:
Article
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