Osteopontin and Developing Kidney
Journal of the Korean Society of Pediatric Nephrology
;
: 1-7, 2006.
Article
Dans Anglais
| WPRIM
| ID: wpr-226655
ABSTRACT
Osteopontin (OPN) is a glycosylated phosphoprotein which mediates cell adhesion and migration, and is produced by bone, macrophages, endothelial cells, and epithelial cells. The many regulatory functions of OPN include bone remodeling, tumor invasion, wound repair, and promotion of cell survival. It is produced by renal tubular epithelial cells, and expression is upregulated in glomerulonephritis, hypertension, ischemic acute renal failure, renal ablation, and UUO. In this review, we discuss about osteopontin in general aspect, expression, role on the development and pathologic condition of neonatal kidney.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plaies et blessures
/
Adhérence cellulaire
/
Survie cellulaire
/
Remodelage osseux
/
Cellules endothéliales
/
Cellules épithéliales
/
Ostéopontine
/
Atteinte rénale aigüe
/
Glomérulonéphrite
/
Hypertension artérielle
langue:
Anglais
Texte intégral:
Journal of the Korean Society of Pediatric Nephrology
Année:
2006
Type:
Article
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