Factors Affecting Treatment Outcome of Graft Infection Following Penetrating Keratoplasty
Korean Journal of Ophthalmology
;
: 301-308, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-229271
ABSTRACT
PURPOSE:
To evaluate the factors affecting treatment outcome of graft infection following penetrating keratoplasty (PKP).METHODS:
In this retrospective study, 28 patients who underwent PKP between January 2005 and January 2013 and who were diagnosed with graft infection were classified into a treatment success group or a treatment failure group. Demographic and clinical characteristics, as well as the results of the microbiologic investigation, were analyzed and compared. A subsequent binary logistic regression analysis was performed to identify the prognostic factors affecting treatment outcome.RESULTS:
Graft infection occurred at a mean of 38.29 +/- 36.16 months (range, 1 to 96 months) after PKP. Seventeen patients developed bacterial keratitis, and 11 patients developed fungal keratitis. Overall, of the 28 patients, nine (32.1%) were classified in the treatment failure group. Multivariate analysis identified pre-existing graft failure (p = 0.019), interval longer than 72 hours between donor death and PKP (p = 0.010), and fungal infection (p = 0.026) as significant risk factors for treatment failure.CONCLUSIONS:
Pre-existing graft failure, extended interval between donor death and PKP, and fungal infection were important risk factors for treatment failure of graft infection following PKP.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Infection de plaie opératoire
/
Infections bactériennes de l'oeil
/
Mycoses oculaires
/
Études rétrospectives
/
Facteurs de risque
/
Kératoplastie transfixiante
/
Résultat thérapeutique
/
Survie du greffon
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Korean Journal of Ophthalmology
Année:
2015
Type:
Article
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