Genetic polymorphism of twelve Y chromosomal short tandem repeat loci in Chinese Hui ethnic group / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 594-597, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-229861
ABSTRACT
<p><b>OBJECTIVE</b>To obtain the genetic polymorphism of Y chromosomal short tandem repeat (Y-STR) loci in Ningxia Hui population.</p><p><b>METHODS</b>Blood samples were collected from 150 unrelated healthy male individuals of Ningxia Hui ethnic group. Twelve Y-STR loci were amplified in one tube by using the PowerPlex System STR Amplification Kit, and the genotypes were determined using Genescan and Genotype software of ABI377 DNA sequencer and the frequency of alleles and haplotypes of Ningxia Hui ethnic was obtained.</p><p><b>RESULTS</b>Seventy-five alleles were observed at 12 Y-STR loci. The frequency ranged from 0.0067-0.7067 and the gene diversity ranged from 0.4446-0.8877. Totally 148 different haplotypes were found, which were unique in 150 males. Two haplotypes were shared by 2 males respectively. The haplotype diversity was 0.9864.</p><p><b>CONCLUSION</b>The 12 Y-STR loci are highly polymorphic in Ningxia Hui population and are suitable for genetics and forensic research.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polymorphisme génétique
/
Haplotypes
/
Ethnies
/
Chine
/
Répétitions microsatellites
/
Chromosomes Y humains
/
Asiatiques
/
Ethnologie
/
Fréquence d'allèle
/
Génétique
Limites du sujet:
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Chinois
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2007
Type:
Article
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