Clinical observation on treatment of 75 mid-late stage cancer patients with yanshu Injection / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 681-684, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-230177
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of Yanshu Injection (YI) used in comprehensive treatment on mid-late stage cancer.</p><p><b>METHODS</b>One hundred and fifty patients with malignant cancer were equally randomized into the comprehensive treatment group (group A) and the control group (group B), both groups were treated systematically according to the NCCN 2005 cancer practice guideline, but 20 ml of YI was given additionally to group A every day.</p><p><b>RESULTS</b>After treatment, the level of plasma CD4 and CD4/CD8 ratio were significantly lower in group B than those in group A (P < 0.05); the response rate (RR) was 32.00% (24/75) and 38.67% (29/75) in group B and A respectively, showing insignificant difference (P>0.05), and the clinical benefit rate (CBR)was 58.67% (44/75) in group A, lower than that in group B (85.33% (64/75), P< 0.05); the quality of life (QOL) in group A was superior to that in group B (P<0.05); and the incidence of main adverse reaction to chemotherapeutic agents was significantly lower in group A as compared to that in group B (P<0.05).</p><p><b>CONCLUSION</b>YI could regulate the function of T-lymphocyte subsets, raise the CBR and QOL and reduce adverse reaction of chemotherapy in patients with mid-late stage cancer.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Quinolizines
/
Thérapeutique
/
Tumeurs du sein
/
Médicaments issus de plantes chinoises
/
Tumeurs du rhinopharynx
/
Sous-populations de lymphocytes T
/
Association thérapeutique
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Alcaloïdes
Type d'étude:
Essai clinique contrôlé
/
Etude diagnostique
/
Guide de pratique
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Integrated Traditional and Western Medicine
Année:
2006
Type:
Article
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