Chemical constituents from ripe fruit of Cornus officinalis / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4605-4609, 2016.
Article
Dans Zh
| WPRIM
| ID: wpr-231014
Responsable en Bibliothèque :
WPRO
ABSTRACT
To investigate the chemical compounds from the fruit of Cornus officinalis, six compounds were isolated and determined by extensive spectroscopic analysis as 6'-O-acetyl-7α-O-ethyl morroniside (1), (-)-isolariciresinol 3α-O-β-D-glucopyranoside(2), apigenin (3), cirsiumaldehyde(4), p-coumaric acid (5), caffeic acid (6). Compound 1 was a new iridoid glucoside,and compounds 2-4 were obtained from the Cornus genus for the first time. Compounds 2-6 were evaluated for the viability of PC12 cells when exposed in conditions of oxygen and glucose deprivation. The MTT results showed that compound 4 increased cell viability moderately in OGD/R treated PC12 cells at the concentration of 1.0 μmol•L⁻¹.
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Indice:
WPRIM
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2016
Type:
Article