HPLC tandem-mass spectrometric analysis of the chemical components and decomposition products of allicin extract of garlic / 药学学报
Acta Pharmaceutica Sinica
;
(12): 74-79, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-232594
ABSTRACT
To analyze the chemical components and decomposition products in allicin extract of garlic, the chemical components screening and identification were made with HPLC-MS/MS method by full scan TIC MS, HPLC retention time, product MS spectra and chemical reference standards. The stability of the extract in water and alcoholic solutions was also investigated. There were five major components in allicin extract which were all identified as thiosulfinates. The extract was stable for at least 3 months when stored at -20 degrees C as water solution, but obvious decomposition was observed with the increase of alcoholic concentration. The decomposition products were also identified by HPLC-MS/MS.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plantes médicinales
/
Acides sulfiniques
/
Thiosulfates
/
Chimie
/
Chromatographie en phase liquide à haute performance
/
Spectrométrie de masse ESI
/
Stabilité de médicament
/
Spectrométrie de masse en tandem
/
Ail
/
Métabolisme
langue:
Chinois
Texte intégral:
Acta Pharmaceutica Sinica
Année:
2009
Type:
Article
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