Comparison of dissolution properties between Ginseng micropowder and common powder / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To compare the dissolution properties of Ginseng micropowder and common powder in vitro and investigate the effect of micronization on dissolution of Ginseng.</p><p><b>METHODS</b>Five ginsenosides including Rg1, Re, Rf, Rb1, and Rb2 were determined by high performance liquid chromatography, and the dissolution curves of Ginseng micropowder and common powder were drawn.</p><p><b>RESULTS</b>The dissolution rates of ginsenosides from micropowder exceeded 90% within 5 min, significantly greater than that from common powder. But when the powders were packed in tea bags, the dissolution rates of ginsenosides were higher from common powder than from micropowder.</p><p><b>CONCLUSION</b>Micronization treatments can promote dissolution of ginsenosides from Ginseng.</p>