Therapeutic effect of deoxyribonucleotidum on acute viral myocarditis / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the therapeutic efficacy of deoxyribonucleotidum in treatment of acute viral myocarditis.</p><p><b>METHODS</b>Eighty-eight patients with acute viral myocarditis were randomized equally into therapeutic group and control group. Patients in the control group were treated with routine treatment and those in the therapeutic group were given deoxyribonucleotidum in addition to routine treatment. After 4 weeks, the total efficacy rate and median time of symptom disappearance were compared between the two groups.</p><p><b>RESULTS</b>The total efficacy rate in the control and therapeutic groups was 79.54% and 95.45% (P=0.049), and the median time of symptom disappearance was 9.5 days and 6.5 days, respectively (P=0.035). Hypotension and mild dizziness were found in 2 patients in the therapeutic group without other severe side effects.</p><p><b>CONCLUSION</b>Deoxyribonucleotidum can improve the therapeutic effect for acute viral myocarditis.</p>