Effect of leukotriene receptor antagonist on cough variant asthma / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the curative effect of leukotriene receptor antagonist on cough variant asthma (CVA).</p><p><b>METHODS</b>Sixty-four CVA patients received treatment with bricany and montelukas and 68 control patients had bricany treatment for 4 weeks. The recurrence rate was observed in the two groups during the follow-up for 6 months.</p><p><b>RESULTS</b>The remission time of two groups were 2.5-/+3.6 and 5.3-/+3.8 days in acute phase, respectively, showing a significant difference between them (P<0.05). The recurrence rate of the two groups within 6 months were 20.09% and 40.87%, respectively, showing also significantly differences (P<0.05).</p><p><b>CONCLUSION</b>Leukotriene receptor antagonist and bricany can effectively control CVA and significantly lower the short-term recurrence rate of CVA.</p>