Application of narrow-band imaging endoscopy in laryngeal malignant lesion biopsy / 中华耳鼻咽喉头颈外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the guiding role of narrow-band imaging endoscopy in laryngeal malignant lesion biopsy.</p><p><b>METHODS</b>From February 2013 to January 2014, 113 patients suspected of laryngeal malignant lesions after electronic nasopharyngolaryngoscope screening were included in the study. The patients were randomly divided into two groups, 58 cases in group A underwent laryngeal tumor biopsies in the white light mode and 55 cases in group B did in NBI mode. The patients were applied with corresponding surgery treatment according to the biopsy results. Postoperative pathologic examination result was as a gold standard for identifing the laryngeal diseases.</p><p><b>RESULTS</b>The positive rate of malignant lesions in group A (71.1%, 32/45) was significantly lower than that in group B (95.4%, 42/44) (χ² = 7.75, P < 0.05); the accurate rate of biopsy in group A (77.6%, 45/58) was significantly lower than that in group B (96.4%, 53/55, χ² = 7.09, P < 0.05) .</p><p><b>CONCLUSION</b>Narrow-band imaging endoscopy can obviously improve in the detection of laryngeal malignant lesion by biopsy.</p>