Twenty-Year Experience of Heart Transplantation: Early and Long-Term Results
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 242-249, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-23452
ABSTRACT
BACKGROUND:
We evaluated early and long-term results after heart transplantation (HTPL).METHODS:
One hundred five consecutive patients (malefemale=8025) who underwent HTPL between 1994 and 2013 were enrolled. Based on the changes in immunosuppressive regimen, the study patients were divided into two groups. Early and long-term clinical outcomes were evaluated and compared between the patients who underwent HTPL before (group E, n=41) and after July 2009 (group L, n=64). The group L patients were older (p<0.001), had higher incidence of hypertension (p=0.001) and chronic kidney disease (p<0.001), and more frequently needed preoperative mechanical ventilation (p=0.027) and mechanical circulatory support (p=0.014) than the group E patients.RESULTS:
Overall operative mortality was 3.8%, and postoperative morbidities included acute kidney injury (n=31), respiratory complications (n=16), reoperation for bleeding (n=15) and wound complications (n=10). There were no significant differences in early results except acute kidney injury between group E and group L patients. Overall survival rates at 1, 5, and 10 years were 83.8%, 67.7%, and 54.9%, respectively, with no significant difference between the two patient groups. Rejection-free rates at 1 and 5 years were 63.0% and 59.7%, respectively; rates were significantly higher in group L than in group E (p<0.001).CONCLUSION:
Despite increased preoperative comorbidities, group L patients showed similar early and long-term outcomes and significantly higher rejection-free rates when compared with group E patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Réintervention
/
Ventilation artificielle
/
Transplantation
/
Plaies et blessures
/
Comorbidité
/
Incidence
/
Taux de survie
/
Mortalité
/
Transplantation cardiaque
/
Insuffisance rénale chronique
Type d'étude:
Etude d'incidence
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
The Korean Journal of Thoracic and Cardiovascular Surgery
Année:
2016
Type:
Article
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