Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1277-1278, 2011.
Article
Dans Chinois
| WPRIM
| ID: wpr-235144
ABSTRACT
<p><b>OBJECTIVE</b>To explore the correlation between serum levels of growth differentiation factor-15 (GDF-15) and Thrombolysis in Myocardial Infarction (TIMI) risk scores in patients with unstable angina pectoris (UA).</p><p><b>METHODS</b>The serum levels of GDF-15 in 97 patients with UA and 30 healthy volunteers were measured using enzyme-linked immunosorbent assay (ELISA) and compared between 3 patient groups with different TIMI scores to analyze relationship between serum GDF-15 levels and TIMI risk scores.</p><p><b>RESULTS</b>The serum levels of GDF-15 in UA patients were significantly higher than those in the healthy volunteers (P<0.01). GDF-15 levels also differed significantly between patients with different TIMI scores (P<0.01), and showed a significant positive correlation to TIMI risk scores.</p><p><b>CONCLUSION</b>Serum levels of GDF-15 can be used as an index for evaluating the severity of UA.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Sang
/
Indice de gravité de la maladie
/
Traitement thrombolytique
/
Appréciation des risques
/
Traitement médicamenteux
/
Facteur-15 de croissance et de différenciation
/
Angor instable
Type d'étude:
Etude d'étiologie
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2011
Type:
Article
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