Effect of Xinmaitong capsule on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 850-852, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-235306
ABSTRACT
<p><b>OBJECTIVE</b>To observe the influence of Xinmaitong capsule (XMT) on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome.</p><p><b>METHOD</b>63 cases were divided by randomized, contrastive assigned to XMT group (n = 31) and control group (n = 32). The serum levels of MMP-9 and hs-CRP before and after treatment in 12 weeks were detected.</p><p><b>RESULT</b>After treatment, the serum levels of MMP-9 in control group had no changed and the levels of hs-CRP reduced. The serum levels of MMP-9 and hs-CRP in XMT group had significantly decreased. The serum levels of MMP-9 and hs-CRP had positive correlation, but had no correlation to levels of serum lipids.</p><p><b>CONCLUSION</b>XMT decreased breakdown of matrix collagen, and inflammatory reaction in the patients of ACS, which may have effect on plaque stabilization.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Plantes médicinales
/
Triglycéride
/
Sang
/
Protéine C-réactive
/
Capsules
/
Médicaments issus de plantes chinoises
/
Chimie
/
Cholestérol
/
Matrix metalloproteinase 9
/
Utilisations thérapeutiques
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2007
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS