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Effect of Xinmaitong capsule on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 850-852, 2007.
Article Dans Chinois | WPRIM | ID: wpr-235306
ABSTRACT
<p><b>OBJECTIVE</b>To observe the influence of Xinmaitong capsule (XMT) on serum matrix metalloproteinases-9, high sensitive C-reactive protein levels in patients with acute coronary syndrome.</p><p><b>METHOD</b>63 cases were divided by randomized, contrastive assigned to XMT group (n = 31) and control group (n = 32). The serum levels of MMP-9 and hs-CRP before and after treatment in 12 weeks were detected.</p><p><b>RESULT</b>After treatment, the serum levels of MMP-9 in control group had no changed and the levels of hs-CRP reduced. The serum levels of MMP-9 and hs-CRP in XMT group had significantly decreased. The serum levels of MMP-9 and hs-CRP had positive correlation, but had no correlation to levels of serum lipids.</p><p><b>CONCLUSION</b>XMT decreased breakdown of matrix collagen, and inflammatory reaction in the patients of ACS, which may have effect on plaque stabilization.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Plantes médicinales / Triglycéride / Sang / Protéine C-réactive / Capsules / Médicaments issus de plantes chinoises / Chimie / Cholestérol / Matrix metalloproteinase 9 / Utilisations thérapeutiques Type d'étude: Essai clinique contrôlé Limites du sujet: Adulte très âgé / Femelle / Humains / Mâle langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2007 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Plantes médicinales / Triglycéride / Sang / Protéine C-réactive / Capsules / Médicaments issus de plantes chinoises / Chimie / Cholestérol / Matrix metalloproteinase 9 / Utilisations thérapeutiques Type d'étude: Essai clinique contrôlé Limites du sujet: Adulte très âgé / Femelle / Humains / Mâle langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2007 Type: Article