Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 733-735, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-240875
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC).</p><p><b>METHODS</b>Sixty-NSCLC patients were randomly divided into the treated group (n = 30, treated with AI combined with chemotherapy) and the control group (n = 30, treated with chemotherapy alone). Chemotherapy of MVP protocol was applied to both groups. AI was supplemented to the treated group by intravenous dripping 60 ml per day. Treatment of 21-28 days as one treatment cycle, and 2-3 treatment cycles were applied.</p><p><b>RESULTS</b>The effective rate in the treated group was 40.0% and in the control group was 36.7%, the mean remission rate in the treated and control group was 5.4 months and 3.3 months, the median survival period 11 months and 7 months, and the 1-year survival rate 46.75% and 30.0%, respectively, the differences of these indexes between the two groups were all significant (P < 0.05). Moreover, the clinical improving rate and QOF elevation rate in the treated group was 80.4% and 43.3%, as compared with those in the control group (50.0% and 23.3% respectively), the difference was also significant (P < 0.01).</p><p><b>CONCLUSION</b>AI combined with chemotherapy can significantly improve the QOF in NSCLC patients of advanced stage.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Qualité de vie
/
Vinblastine
/
Médicaments issus de plantes chinoises
/
Carcinome épidermoïde
/
Protocoles de polychimiothérapie antinéoplasique
/
Cisplatine
/
Carcinome pulmonaire non à petites cellules
/
Astragalus membranaceus
/
Utilisations thérapeutiques
/
Traitement médicamenteux
Type d'étude:
Guide de pratique
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Integrated Traditional and Western Medicine
Année:
2003
Type:
Article
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