Blood pressure changes of elderly hypertensive patients during dental extraction under sedation with continuous intravenous infusion of midazolam / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
;
(4): 132-135, 2007.
Article
Dans Anglais
| WPRIM
| ID: wpr-243542
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the changes in blood pressure (BP) of elderly hypertensive patients having dental extraction under sedation with continuous intravenous infusion of midazolam.</p><p><b>METHODS</b>One hundred elderly hypertensive patients undergoing dental extraction were recruited for this single-blind, randomized, controlled study. Patients in intervention group (n = 50) were given midazolam dissolved in glucose solution and patients in control group (n = 50) were given glucose solution only with communication technique. Systolic BP (SBP) and diastolic BP (DBP) were recorded in five time points.</p><p><b>RESULTS</b>Under basal conditions, intervention group did not show significant difference in BP compared with control group. Before sedation, mean values of SBP and DBP (especially SBP) significantly increased compared with basal conditions in both groups (P < 0.05). During dental extraction sessions, mean values of BP in intervention group significantly decreased than control group (P < 0.05), but coefficient of variation did show significant difference in both groups.</p><p><b>CONCLUSION</b>Continuous intravenous infusion of midazolam has been proved to be very successful in controlling BP of elderly patients having dental extraction.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pharmacologie
/
Physiologie
/
Systole
/
Extraction dentaire
/
Pression sanguine
/
Perfusions veineuses
/
Midazolam
/
Utilisations thérapeutiques
/
Diastole
/
Hypertension artérielle
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Adulte très âgé
/
Humains
langue:
Anglais
Texte intégral:
Chinese Medical Sciences Journal
Année:
2007
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS