Crossing anastomosis of nerve bundles near innervated organs to treat irreparable nerve injuries / 中国医学科学杂志(英文版)

ABSTRACT

<p><b>OBJECTIVE</b>To study the therapeutical effects of crossing anastomosis of nerve on the peripheral and central nerve injuries.</p><p><b>METHODS</b>Twelve kinds of central and peripheral nerve disorders and their complications were treated with 11 kinds of crossing anastomosis of nerve bundles near the innervated organs. After nerve injury and repair, somatosensory evoked potentials (SEPs) and horseradish peroxidase (HRP) retrograde tracing studies were used to investigate the rabbit's nerve function and morphology.</p><p><b>RESULTS</b>The ulcers of all patients healed. Sensation, voluntary movement, and joint function recovered. Four weeks after the anastomosis of distal stump of radialis superficialis nerve and median nerve, pain sensation regained and SEPs appeared. HRP retrograde tracing studies demonstrated sensory nerve ending of medial nerve formed new connection with the body of neuron.</p><p><b>CONCLUSION</b>Crossing anastomosis of nerve is an effective method to treat peripheral and central nerve injuries.</p>