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Predictors of Recovery of Left Ventricular Systolic Dysfunction after Acute Myocardial Infarction: From the Korean Acute Myocardial Infarction Registry and Korean Myocardial Infarction Registry
Korean Circulation Journal ; : 527-533, 2013.
Article de En | WPRIM | ID: wpr-24544
Bibliothèque responsable: WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES: We investigated the predictors of the recovery of depressed left ventricular ejection fraction (LVEF) in patients with moderate or severe left ventricular (LV) systolic dysfunction after acute myocardial infarction (MI). SUBJECTS AND METHODS: We analyzed 1307 patients, who had moderately or severely depressed LVEF ( or =45%). RESULTS: Recovery of LV systolic dysfunction was observed in 51% of the subjects (group II, n=663; DeltaLVEF, 16.2+/-9.3%), whereas there was no recovery in the remaining subjects (group I, n=644; DeltaLVEF, 0.6+/-7.1%). In the multivariate analysis, independent predictors of recovery of depressed LVEF were as follows {odds ratio (OR) [95% confidence interval (CI)]}: moderate systolic dysfunction {LVEF > or =30% and <45%; 1.73 (1.12-2.67)}, Killip class I-II {1.52 (1.06-2.18)}, no need for diuretics {1.59 (1.19-2.12)}, non-ST-segment elevation MI {1.55 (1.12-2.16)}, lower peak troponin I level {<24 ng/mL, median value; 1.55 (1.16-2.07)}, single-vessel disease {1.53 (1.13-2.06)}, and non-left anterior descending (LAD) culprit lesion {1.50 (1.09-2.06)}. In addition, the use of statin was independently associated with a recovery of LV systolic dysfunction {OR (95% CI), 1.46 (1.07-2.00)}. CONCLUSION: Future contractile recovery of LV systolic dysfunction following acute MI was significantly related with less severe heart failure at the time of presentation, a smaller extent of myonecrosis, or non-LAD culprit lesions rather than LAD lesions.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Pronostic / Débit systolique / Échocardiographie / Analyse multifactorielle / Études de suivi / Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase / Troponine I / Diurétiques / Défaillance cardiaque / Corée Type d'étude: Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Humans Pays comme sujet: Asia langue: En Texte intégral: Korean Circulation Journal Année: 2013 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Pronostic / Débit systolique / Échocardiographie / Analyse multifactorielle / Études de suivi / Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase / Troponine I / Diurétiques / Défaillance cardiaque / Corée Type d'étude: Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Humans Pays comme sujet: Asia langue: En Texte intégral: Korean Circulation Journal Année: 2013 Type: Article