Clinical related factors of portal vein tumor thrombosis in patients with hepatocellular carcinoma: a logistic regression analysis / 中华外科杂志
Chinese Journal of Surgery
;
(12): 733-736, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-245541
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the related factors of portal vein tumor thrombosis (PVTT) in patients with HCC.</p><p><b>METHODS</b>A total number of 234 patients with hepatocellular carcinoma (HCC) were included in this retrospective study. Uni-variate and multi-variate logistic regression analysis were employed to analyze the association between PVTT and 18 routine clinical parameters.</p><p><b>RESULTS</b>Among the 234 patients with HCC, 15% of patients (35/235) had PVTT. Univariate logistic regression analysis revealed significant association of age (P = 0.016), gamma glutamyl transferase (GGT, P = 0.003), number of segmental invasion (P = 0.007), microvascular invasion (P < 0.01), segment location of S2 (P = 0.001), S3 (P = 0.000), S4 (P = 0.004) and S6 (P = 0.016). Multivariate analysis shows potential significant predictors of PVTT in HCC were age (RR 0.373; 95% CI 0.146-0.954; P = 0.040), the tumor location of S3 (RR 4.625; 95% CI 1.916-11. 165;P = 0.001), GGT (RR 4.091; 95% CI 1.448-11.553; P = 0.008) and microvascular invasion (RR 20.912; 95% CI 4.745-92.172; P < 0.01).</p><p><b>CONCLUSIONS</b>PVTT occurred more commonly in the younger (< 50 years old), and those with high level of GGT, segment location of S3 and microvascular invasion.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Veine porte
/
Modèles logistiques
/
Études rétrospectives
/
Facteurs de risque
/
Études de suivi
/
Carcinome hépatocellulaire
/
Embolie
/
Tumeurs du foie
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Aged80
/
Enfant
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Surgery
Année:
2008
Type:
Article
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