Formulation and process optimization of formula Qiqi pellets prepared by extrusion-spheronization / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To prepare traditional Chinese medicine formula Qiqi pellets by extrusion-spheronization and study the optimal formulation and process.</p><p><b>METHOD</b>Qiqi pellets were prepared by a new style extrusion-spheronization equipment, the optimal formulation and process was obtained by the studies of influenitial factors and L9 (3(4)) orthogonal design, the micromeritic properties and product yield of pellets were determined.</p><p><b>RESULT</b>The formula Qiqi pellets prepared by extrusion-spheronization were all spheral with smooth surface; the product yield was high.</p><p><b>CONCLUSION</b>Extrusion-spheronization was suitable to produce Chinese Herbal Medicine pellets. The preparation process was simple and feasible; The quality of the prepared pellets was excellent. It was worth further study.</p>