Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection / 대한해부학회지
Anatomy & Cell Biology
;
: 331-336, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-24635
ABSTRACT
Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Techniques de reproduction
/
Taux de grossesse
/
Injections intracytoplasmiques de spermatozoïdes
/
Milieux de culture
/
Techniques de reproduction assistée
/
Structures de l'embryon
/
Antigènes HLA-G
/
Leucocytes
Limites du sujet:
Humains
/
Grossesse
langue:
Anglais
Texte intégral:
Anatomy & Cell Biology
Année:
2011
Type:
Article
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