Research Progress on CALR Mutation in the Myeloproliterative Neoplasm -Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1252-1255, 2016.
Article
Dans Chinois
| WPRIM
| ID: wpr-246781
ABSTRACT
There is no gold diagnostic standard for BCR-ABL fusion gene negative chronic myeloproliterative neoplasm(cMPN). The following detection methods such as comprehensive bone marrow cell morphology, bone marrow pathology, genetic mutation, flow cytometry and immunohistochemical are needed to diagnose the BCR-ABL fusion gene positive cMPN. The JAK2 mutation can be used as a specific diagnostic criteria for polycythemia vera (PV), but there is no specific and sensitive indication for the JAK2 mutation-negative MPN. CALR mutation would be an indication in a certain extent. In this review, the CALR mutation detection, detection mean and its correlation with disease diagnosis and prognosis etc were summarized.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Moelle osseuse
/
Cellules de la moelle osseuse
/
Calréticuline
/
Mutation
/
Syndromes myéloprolifératifs
Type d'étude:
Étude pronostique
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2016
Type:
Article
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